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News: This Genetic Defect Could Be Why Typhoid Mary Never Got Typhoid Fever

Whether or not a microbe is successful at establishing an infection depends both on the microbe and the host. Scientists from Duke found that a single DNA change can allow Salmonella typhi, the bacteria that causes typhoid fever, to invade cells. That single genetic variation increased the amount of cholesterol on cell membranes that Salmonella and other bacteria use as a docking station to attach to a cell to invade it. They also found that common cholesterol-lowering drugs protected zebrafi...

News: What Are Superbugs? Everything You Need to Know About Antibiotic Resistance

Joe McKenna died when he was 30 years old. A young married man with his future ahead of him, he was cleaning up the station where he worked as a fireman. Struck by a piece of equipment fallen from a shelf, Joe complained of a sore shoulder. Over the next week, Joe worsened and ended up in the hospital. Chilled, feverish, and delirious, his organs shut down from an infection we'd now call septic shock.

How To: Model a head in 3D using Maya edge extrusion method

Modeling a face using Maya or any other 3D art program is tough to do without having the result end up looking like a zombie. See the film Final Fantasy: The Spirit Within if you don't know what I'm talking about. This six-part video will help you avoid this problem in your own 3D models by teaching you how to 3D model a face using the head extrusion method in Maya. You'll need a photo to start with (the creator does not supply the one he used here) but once you have that you should be able t...

How To: Play "Lua" by Bright Eyes on the ukulele

Want to play Bright Eyes' "Lua" on the ukulele? Learn how with this free video ukulele lesson from Ukulele Mike. Whether you play the ukulele or bass kazoo, there is no better way to improve your chops than by learning to play your favorite songs. Not only is it more fun and much easier than running drills or memorizing a chord book by wrote, it's obviously also a wonderful way to build your repertory of songs. For more information, and to get started playing this indie folk song on your own ...

How To: Maintain car tires and ensure maximum tire life

This video shows you how to perform tire maintenance on your vehicle. In order to check the tread wear on your tires, you will need a penny. You will have to check the entire tire for wear, because tires may wear away unequally. Just slip the penny between the tread. If you are still able to see Lincoln’s entire head, then you will need to replace your tire(s).

How To: Choose fruit trees

Doña Ana County Extension Agent John White and Master Gardener Benny Knudsen look at stone fruit trees on their tour of the "Garden of Weeden". The Mariposa Plum, the dwarf Stella Sweet Cherry, Elberta Peach, Tilton Apricot and the almond tree (which also belongs to the stone fruit family) are featured in this segment of Southwest Yard and Garden series. The suitability of these trees for a small garden is mentioned. Besides this, also discussed is the problem of late frost and its effect on ...

How To: Grow blue corn

Blue corn is a special variety of corn which can be differentiated by the majority of the corn species by looking at the unusual top growth of the corn. It is a hybrid and grows very uniformly throughout. Now take a corn from the field and peel it off. You shall notice that it has a blue color corns. Blue color corns are hard from outside but they are very soft and tender in the middle. You can use these blue corns in making commercial products like blue corn chips, tortillas, and atole ’,‘ c...

How To: Improve your spins in dance

Component 1. Frame And Posture. The benefits of dance shoes never outweigh the benefits of proper spin technique. Your body should be straight lower abs and stomach should be tight. Your arms are in proper position. If you lift your hand it should be in 90 degree angle.

How To: Use sidechain autofilter effects in Ableton

Open your program to a new live set. By using three keys (in Ableton Live), Command (Ctrl), Shift and t, you can create a short cut. Create two new midi tracks making one for (side chain) bass and one for (side chain) kick. To rename a track choose the two keys Command (Ctrl) and r. Next, you can load up the presets, located on the side bar list, one a bass, and, then a basic kick drum by opening up impulse, electronics and Tremor 1994. Now create a couple of patterns. To do this go an empty ...

How To: Use a damper pedal whle playing piano

Enthusiastic, young David Yzhaki teaches you how to play the piano with a damper (sustain) pedal. Get to know the pedals on an upright piano. The right pedal, which is the primary focus of the video, is the sustain pedal, which creates a sustaining note when pressed. The left pedal is called the "una corda," which modifies the tone quality by softening the note when pressed. The middle pedal is called the sostenuto pedal, which enables the piano player to hold a note longer than usual. To use...

How To: Create flooring in Photoshop

Pixel Perfect is the "perfect" show to help you with your Photoshop skills. Be amazed and learn as master digital artist Bert Monroy takes a stylus and a digital pad and treats it as Monet and Picasso do with oil and canvas. Learn the tips and tricks you need to whip those digital pictures into shape with Adobe Photoshop and Illustrator. In this episode, Ben shows you how to create flooring in Photoshop.

How To: Apply localized correction in Lightroom 2

Pixel Perfect is the "perfect" show to help you with your Photoshop skills. Be amazed and learn as master digital artist Bert Monroy takes a stylus and a digital pad and treats it as Monet and Picasso do with oil and canvas. Learn the tips and tricks you need to whip those digital pictures into shape with Adobe Photoshop and Illustrator. In this episode, Ben shows you how to apply localized correction in Lightroom 2.

How To: Make pecorino cheese & pancetta spaghetti carbonara

Rick Stein teaches you how to open a packet of pasta in a true Italian style whilst talking through a delicious spaghetti carbonara with pecorino cheese and pancetta. Great recipe clip from BBC cookery show 'Rick Stein's Mediterranean Escape'. Garlic, parsley, pancetta, eggs, pecorino and spaghetti. Quick and simple to make!

How To: Master the gusset stitch for knitting

Stay tuned for this knitting instructional video on the gusset stitch. When you knit the heel flap, you slipped a stitch at the beginning of each row. This made a very nice chain through which you can pick up the gusset stitches. You can either pick up stitches through the whole chain stitch, or through the back loop of the chain stitch. Picking up stitches through the whole chain stitch creates a rather definite seam on the inside which could be uncomfortable to wear. I prefer to pick up the...

How To: Insert a heel when knitting a sock

Stay tuned for this knitting instructional video on inserting a heel for a knitted sock. This is a very large scale knitted sock. It's going to be a felted Christmas stocking. The knitting is finished except for inserting the heel. The knitting technique demonstrated is exactly the same for a more normal, human-size knitted sock. It's also the same technique used to insert a pocket in a sweater.

How To: Improve your fuel efficiency

Getting the most mileage out of your car is especially important now that gas prices are rising. Learn how you can improve your fuel efficiency and the gas mileage of your car with the tips from this how to video from the DIY network. Save a some money the next time at the pump with this gas saving tutorial.

How To: Use a Powder Vibe tool for glass enamel powders

The Powder Vibe tool is a motorized device for the dispensing of glass enamel powders. This tool helps with health and safety by reducing dust and the need for enamel powder sifting when lampworking glass jewelry. The powder vibe tool keeps your enamel powders clean and gives you great control. Use the tool to add smooth streams of glass powder and enamel powder onto your lampwork glass beads.

How To: Brew Japanese gyokuro green tea

Green tea tastes great and it does wonders for your health. In this how to video Griff and Matt will show you how to Make a special kind of green tea called Gyokuro. Gyokuro is a fine Japanese tea. Watch and learn how the Japanese brew gyokuro tea to perfection.