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News: Replacement Joints with Antibiotics on Board Mean Lower Chance of Infection & Fewer Surgeries

For about a million Americans each year, a joint replacement brings relief from pain and restored mobility. But, 5–10% of those people have to endure another surgery within seven years, and most of those are due to an infection in their new joint. If doctors could treat infections more effectively, patients could avoid a second surgery, more pain, and another rehabilitation.

News: How Gut Bacteria Could Set Off the Immune System in Rheumatoid Arthritis

As if the swollen, painful joints of rheumatoid arthritis weren't enough, the disease is the result of our immune system turning against cells of our own body. Ever since this realization, scientists have worked to find the trigger that sets the immune system off. Scientists believe that gut bacteria may have a role in initiating the abnormal immune response. Now, a team of researchers from Boston has figured out how that might occur.

News: How Parental Choice Not to Vaccinate Kids Starts and Spreads Pertussis Outbreaks

It's not always easy to get to the root of an infection outbreak. Epidemiologists study infected people, contacts, and carefully examine where the infections happened and when. In the case of a 2012 outbreak of pertussis — whooping cough — in Oregon, scientists just published an analysis of how vaccination status affected when a child became infected during the outbreak.

News: Scientists Discover How to Track Down HIV's Hiding Spots—A Potential Pathway to a Cure

Tremendous strides have been made in the treatment and outlook for patients infected with HIV, the human immunodeficiency virus. Treatment with a combination of antiretroviral drugs can keep patients with HIV alive for decades, without symptoms of the infection. The trouble is, if HIV-infected people stop taking their medications, the virus takes over in full force again—because the virus hides out quietly in cells of the immune system, kept in check, but not killed by the treatment.