In this video tutorial, Chris Pels shows how to use the ASP.NET IIS Registration Tool to configure ASP.NET. First, see how file extensions are mapped to ASP.NET in the IIS Manager on a global and web-site-by-web site basis. These script maps provide the basis for configuring individual ASP.NET applications to run under a specific version of the .NET Framework. Next, see how aspnet_regiis.exe, the IIS Registration Tool command line utility, is specific to each version of the .NET Framework and...
If you have a taste for sweets, you have at least one thing in common with mosquitoes. While too much sugar is unhealthy for humans, a new product makes sweets deadly to mosquitoes.
A vaccine against HIV might prevent the disease that we can't seem to cure. Some HIV patients make antibodies that can take down the virus, much the way a vaccine might. But, scientists haven't been able to provoke that type of response in other people. However, in a process that might work in humans, a group of researchers has successfully generated antibodies in cows that neutralize multiple strains of HIV.
Cancer cells do a pretty good job of flying under the radar of our immune system. They don't raise the alarm bells signaling they are a foreign invader the way viruses do. That might be something scientists can change, though.
Heart disease is the leading cause of death of men and women in the US. Over half a million Americans die from it annually. Atherosclerosis — a build up of plaque in the arteries — is a common feature of heart disease and can be caused by smoking, fats and cholesterol in the blood, diabetes, and high blood pressure.
Dengue fever is a danger to anyone living or visiting tropical or subtropical regions. It can be hard to detect the infection in its earliest and most treatable phase, especially in children. Luckily, new research highlights better techniques for triaging the disease in infected children with more severe symptoms, potentially saving lives.
Sepsis is not only a gross sounding word but also a deceptively dangerous and fatal infection. Which is why more than 40 hospitals nationwide are coming together to a new collaboration to help reduce sepsis mortality, named Improving Pediatric Sepsis Outcomes (IPSO).
We can add one more health effect of our gut bacteria to the growing list. Researchers from the UK have just reported that the gut microbiota plays a role, both directly and indirectly, on the toxicity and efficacy of chemotherapy. Their findings are published online in the journal Nature Reviews Gastroenterology & Hepatology.
Yellow fever has emerged again in Brazil, causing death and disease to people unprepared for this mosquito-borne illness.
For some, drinking raw milk is a way to get back to nature, improve family nutrition, and hedge against asthma and allergies. However, according to public health authorities, drinking raw or unpasteurized milk is a big mistake—even fatal. So what's the story?
Transmitted by a sandfly one-third the size of a mosquito, parasitic Leishmania protozoa are responsible for a flesh-destroying disease that kills an estimated 20,000 people per year. Two new studies offer understanding of how the parasite provides immunity through persistence and why some people suffer more virulent forms of the disease.
In the summer of 1976, 4,000 American Legionnaires descended upon the Bellevue-Stratford Hotel in Philadelphia, Pennsylvania, for a four-day convention. Several days later, many of the attendees experienced symptoms of severe pneumonia. By the beginning of August, 22 people had died. The Centers for Disease Control and Prevention (CDC) estimate that about 180 people were sickened and 29 people died before this mysterious outbreak burnt out.
Using mathematical modeling, researchers suggest weather and warming created the "perfect storm" that drove the Zika outbreak in 2016.
New weapons are needed to combat antibiotic-resistant bacteria. Instead of drugs, scientists have discovered in an animal study that they may be able to harness vampire bacteria to vanquish pneumonia.
A virus easily spread among trout and salmon could make it harder to keep your favorite fish on the menu.
Rising on the world stage, dengue fever is transmitted by mosquitoes — and apparently air travel too.
With a death rate of one in five, sepsis is a fast-moving medical nightmare. New testing methods might improve your odds of survival if this infection ever hits you.
As our cells age, they eventually mature and die. As they die, they alert nearby cells to grow and multiply to replace them. Using a special imaging process that combines video and microscopy, scientists have observed the cellular communication between dying and neighboring cells for the first time, and think they may be able to use their new-found information against cancer cells, whose damaged genomes let them escape the normal dying process.
It is not just a bad summer for ticks — it has been a bad decade for the spread of tick-borne infections. New surveillance from the CDC reports rapid expansion and increase in cases of babesiosis, a sometimes life-threatening disease, in Wisconsin.
Bone loss and belly fat may no longer be certain fates of menopause, thanks to new research from an international team of scientists.
The Centers for Disease Control and Prevention estimated that there were 212 million cases of malaria across the world in 2015, and 429,000 of those people died — mostly children living in Africa. Preventing and treating those infections has been a challenging world priority. That makes a new malaria drug discovery — published in Science Translational Medicine — incredibly important.
Wound infections don't usually enter the blood and become systemic, spreading the infection throughout our bodies, and there's a good reason for that: Our bodies actively work to prevent it, according to research that discovered a new use for a protein first discovered decades ago.
Even though the Ebola virus was discovered as recently as 1976, over 30,000 people have been infected since, and half have died a horrible death. Since there's no way to cure the infection, the world desperately needs a way to prevent it — and the five similar viruses in its family, the ebolaviruses.
US blood banks have assured the American public that they have the tools to prevent a Zika contamination, despite the rapid spread of the disease.
It's happened to all iOS users: You're talking to a friend or watching TV, and all of a sudden, you hear "I'm not quite sure what you've said." Apparently, your phone heard something that resembled "Hey, Siri," and activated the assistant. But now, thanks to a new patent from Apple, the days of unexpected Siri may be numbered.
Officials in Colorado are concerned as 61 cases of the mumps were reported so far this year, a significant increase in the prevalence of the contagious disease in the state.
A sometimes serious disease spread by fleas is making inroads in Texas, quietly doubling case numbers since 2008, and beginning to encroach on larger metropolitan areas.
We may not fully appreciate all the important roles wheat plays in our lives until it's gone—or at least, when it's in very short supply. What would a world be like without bread, cakes, cereal, pasta, or wheat beer? If the dire warnings about an impending stem rust fungus come to pass, we may know all too soon.
A new study just out reveals that HIV takes hold in the human body with the help of cells that usually work to heal, not kill.
In this video, we learn how to write a winning resume and cover letter. First, you want to remember that your resume online needs to be keyword rich, so you will have greater chances of getting an interview. To find keywords for your resume, look up different job descriptions to change your resume to fit that specific job. List your specific qualities that make you the best candidate for that job. For your cover letter, make sure you always send it along with your resume. You want to capture ...
New to Excel? Looking for a tip? How about a tip so mind-blowingly useful as to qualify as a magic trick? You're in luck. In this Excel tutorial from ExcelIsFun, the 180th installment in their series of digital spreadsheet magic tricks, you'll learn how to count specific words, specific numbers, numbers greater than a hurdle, numbers between two values, values that are NOT equal to an amount, words that end in es, all words, all numbers, all content, all blanks, all things which aren't words ...
This six minute video shows you how to sell your car on craigslist. First, go to craigslist.com and click on the nearest city (or country). Follow the links to list an ad for a car for sale. You will want to put the kind of car in the posting title because that is used in sorting search results. In the posting description it is important to be as specific as possible - again describing the car, giving some history of the car like if it has ever been in an accident and if you have had any work...
Adjusting the color of specific objects within your images in Photoshop is crucial. Sometimes fine tuning the color of just one component in an image is required. While an image may be adjusted globally at once, this approach lacks flexibility. This tutorial will show you the proper steps from the creation of an adjustment layer to the appropriate and functional calibration of the hue and saturation options. Get the most out of these tools and maximize your productivity in Photoshop.
The Red One Camera has three buttons labeled A B and C on the back of the camera. Each of these buttons have a specific feature that is the default setting. Learn what these buttons do.
Find out how to use the powerful search functions in WonderHowTo. Learn how to refine your search to specific categories and subcategories.
Appendicitis is one of the most painful and potentially dangerous maladies that can afflict a modern Western person, and recognizing the symptoms early is key to treating the disease and ending the pain. Watch this video for signs to looks for to tell if you or someone else is suffering from appendicitis. If they are, get them to the hospital now.
In this video tutorial, viewers learn how to zoom in and out on a Mac computer. To access the zooming tool, begin by clicking on the Apple menu and select System Preferences. Under System, select Universal Access and check On under Zoom. In Options, users are able to set specific settings such as the maximum and minimum range of zoom. The keyboard shortcut for zooming in is: Option, Command and =. The keyboard shortcut for zooming out is: Option, Command and -. This video will benefit those v...
This video teaches you how to become a DJ. In this session we can learn how to keep the beat off beat by keeping the timing of the beats the same. This video shows the specific way of increasing the beats and decreasing the beats according to the tracks that are played. This tutorial also has a live sample of how a beat can be matched off and a how to maintain a constant interval between the beats. It also has some specific instructions on how to maintain a constant interval between the track...
There are a lot of things that can cause decline in plants. Some are caused by insects or diseases and some are caused by environmental conditions, known as abiotic factors. Consequently, it can be hard to diagnose which, or what combination, of the above factors are resposnible for the poor health of your plant. In this green video tutorial, you'll learn how to troubleshoot plant problems. To learn what it takes, take a look.
The U.S. Centers for Disease Control estimates that 73,000 people contract E. coli O157:H7 each year. The primary source of these illnesses is ground beef that has been improperly handled and cooked. Watch this video to learn how you can avoid the spread of this bacteria.