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How To: Perform single cell electroporation of neurons

Single-cell electroporation (SCE) is a specialized technique allowing the delivery of DNA or other macromolecules into individual cells within intact tissue, including in vivo preparations. The distinct advantage of this technique is that experimental manipulations may be performed on individual cells while leaving the surrounding tissue unaltered, thereby distinguishing cell-autonomous effects from those resulting from global treatments. When combined with advanced in vivo imaging techniques...

Altruistic Hacking: The Rise of the DIY Radiation Detector

Understandably, the tragedy in Japan has substantially risen the level of worldwide radiation-related hysteria. So much so, as an alternative to stampeding health food stores for iodine tablets, crafty individuals and organizations are hacking together personal radiation detectors. Rather than relying on the government, the creation and modification of handheld Geiger counters provides a self-sufficient solution to today's questions regarding radiation. Profiled below, three admirable organiz...

How To: Create a procedural night sky with stars in Autodesk 3ds Max

This tutorial walks you through how to set up a procedural night sky with twinkling stars in Autodesk 3ds Max. You will be creating a opacity material with noise maps, and using an phase animated noise behind this to illuminate the stars. To edit the star size and brightness, you should play with the noise size and high/low settings on the individual noise map. Whether you're new to the Blender Foundation's popular open-source 3D computer graphics application or are a seasoned digital artist ...

How To: Give a professional level foot massage to your partner

Our feet take a beating in daily life. Who wouldn't want to lay down at the end of the day and receive a foot massage? Follow this three part, professional style tutorial and learn how to really take a load off those aching toes. This tutorial covers everything from ankles, to stroking the whole foot and down to the individual toes. Practice makes perfect and I'm sure your partner will appreciate the effort! Give a professional level foot massage to your partner - Part 1 of 3.

News: Police Use iPhones to ID Suspects via Face, Iris and Fingerprint Scans

Some cops already have the ability to extract data from your cell phone using handheld forensic devices, but soon police officers will have a new mobile data collection toy to play with—an Apple iPhone. Actually, it's an iPhone-based device that connects directly to the back of an iPhone, which is designed to give law enforcement an accurate and immediate identification of a suspect based on their facial features, fingerprints and even their eyes.

How To: Create and use groups in 3ds Max

One of the object association types in 3ds Max is groups. In this video tutorial we will learn how to create the relationship in 3DS Max. The author compares groups to dating, where each individual has higher commitment yet they still retain their own identity. Whether you're new to Autodesk's popular modeling software or a seasoned 3D artist just looking to better acquaint yourself with the application, you're sure to be well served by this video tutorial. For more information, take a look! ...

How To: Block your cell phone number

Ross Handler shows us how to block your cell phone number for outgoing calls. First call your provider and let them know you want all of your outgoing calls to not be registered onto some one else's caller I.D. They will gladly do that for you. But if you want to just block individual calls, and not all your outgoing calls, dial *67 before dialing in the person your calling's phone number. You will not hear a 'beep' when you are dialing *67, but keep proceeding and the call will go through an...

How To: Make noodle kugel aka noodle pudding

Louisa Kasdon has another great Jewish side dish recipe for us. Noodle kugel is a favorite comfort food, especially in cold winters. It's got a little of everything thrown in, and can easily be adapted to individual tastes. In this video, she shows us how to make a version of noodle kugel with sour cream and cream cheese. Mmm...carbs and dairy - sounds like a recipe for yumminess!

How To: Use effectors in MoGraph for CINEMA 4D

In the first part of this two-part tutorial on using effectors in MoGraph for CINEMA 4D, Mylenium goes over the general features and parameters that are common amongst the effectors. Part two covers how to use the specific features of each individual effector. Use effectors in MoGraph for CINEMA 4D - Part 1 of 2.

The Joy of Destruction: Smashing, Guillotining, Igniting & More

Why is it so satisfying to squash, snap, squeeze and splatter? You know, squashing a juicy grape, snapping a twig, squeezing ketchup out of a packet—perhaps with your fist—or splattering mud across a sidewalk. But all of these actions are child's play next to animators Laura Junger and Xaver Xylophon's Joy of Destruction. The real joy of destruction is illustrated below—we're talking sawing ladies in half, exploding corn into popcorn with dynamite, burning cities, and rolling over statues wit...

News: Oxy Acetylene Spark Plug

I first wanted to say I think its really cool what you guys are doing being involved with your fans. I learned this in the oil field, what you do is use an oxy-acetylene mixture which can be acquired from any cutting torch. You fill plastic bags or gatorade bottles or whatever with the mixture then take out the spark plugs from the engine block of a vehicle and tape the bags or bottles to the spark plugs of a truck. When the individual turns on the pickup and when each plug fires will be a sm...

News: Alligator Zoo Drowning

The idea is to get at least three of the guys to go to a zoo with an indoor alligator pond inside one of the indoor buildings with a railing around the pond. The pond needs to be murky and anyone looking down at the pond should not be able to see more than a foot down in the water. A fake alligator head on a hydroaulic cylinder will be floating at the surface near one side of the pond as that is usually all you can see of an alligator when it is wallowing in the water anyway. A scuba diver wi...

How To: Make a no sew fleece blanket

In this tutorial, we learn how to make a no sew fleece blanket. First, you will need to purchase fleece in a large size, large enough to be a comfortable blanket. Next, lay the fleece flat down and cut fringe down on two sides, four inches apart. On the other two sides (opposite from each other), cut fringe one inch between each other. Next, tie your one inch fringes into individual knots. These are great blankets to make for charity, because they are not only soft and warm, they are inexpens...

How To: Create a shotgun blast using 3ds Max and After Effects

In this 2 part tutorial, Michael Park will demonstrate how to create a shotgun blast at the camera using 3D rendered particles and distortion trails along with some 2D footage to create a convincing effect. In part 1 of this tutorial, we will use 3ds Max to create the 3D shotgun pellet geometry and material, as well as the distortion trails to be later used in the After Effects composition. In part two Michael will add the 3D footage together with 2D footage in After effects and use different...

How To: Make chocolate fondant

A treat for chocolate lovers of the highest order. Omri Shahar, formerly chef at New York's Union Pacific Restaurant shows you how to make an individual sized hot fluffy chocolate cake with a silky warm chocolate liquid middle. It's easy and you can make a Michelin star level dessert at home with no fuss. Enjoy! Savour this Chocolate Fondant recipe. Make chocolate fondant.

How To: Bulk Delete Messages Faster with This Hidden iOS 13 Gesture

On the surface, deleting conversations in Messages seems harder in iOS 13 after Apple removed the "Edit" button on the main page. Fortunately, they added a new gesture that lets you remove entire threads and individual messages with ease.

News: Jewelry Made With Hair and Dead People

No exaggeration in today's headline, design student Anna Schwamborn has actually designed a jewelry line made from the hair and cremated ashes of dead loved ones. Human hair sure makes a nice accent to the black bone china (note the word "bone" - human ashes are mixed in).

News: Creepy Talking-Piano Hack

Austrian composer Peter Ablinger has created a "speaking" piano. Ablinger digitized a child's voice reciting the Proclamation of the European Environmental Criminal Court to "play" on the piano via MIDI sequencer.  Apparently, the computer is connected to the piano, which analyzes the human speech, and then converts it to key-tapping.

News: The 7 Best Secret Features of iOS 5

Just installed the new iOS 5 on your iPad, iPhone or iPod touch? There's a lot of great features to check out and play around with. After messing around with it on my iPhone 4 for a few minutes, these seven additions caught my attention. Check them out below—and tell us what your favorite new features are in the comments below.

News: Need help

everytime i ask for help, if i need it from friends, my page get stuck (freezes) i can no longer ask friends for help or even when i have to individuals the page freezes, i am stuck waiting for other to ask me for help in order to collect certain items for missions, :-( how do i get past this, the other problem is at one time i could to to my games requests to accept every thing then at the bottom of it all i could see requests from my neighbours for specific games i can;t do that i=either, h...

News: Massive 30 Foot Tall Shmup Game 'Rocket Bullet Storm' Hits Hungary

Hungarian developer Nemesys Games is best known for making the lighthearted Fortix series, a pair of casual tower defense variants available on Steam. For their latest project, they've decided to expand their horizons, going beyond downloadable sawbuck games. It's called Rocket Bullet Storm, a chaotic old-school shmup similar to the surprising number of others to come out in the last year. The difference is that this one is huge—30 feet tall—and consumes 250 square meters of floorspace, which...

News: "Living" Flower Dresses Change With the Seasons

While I don't find Mattijs van Bergen and Anouk Vogel's "Living" dresses aesthetically earth shattering, I'm wowed by the concept. The fashion designer and landscape architect created a collection of dresses made from recycled inner tubes and flowers for a late summer exhibition titled “Fashion & Architecture” at the Amsterdam Centre for Architecture.

How To: Use QuickBooks assistance

In this video, we learn how to use QuickBooks assistance. The assistance gives you answers to problems that you may be having with their software. This is a great way to learn the basics, like individual tasks that are on the home page. The coach was made for someone who is brand new to QuickBooks, so the information may be introductory instead of advanced. You can also go to a QuickBooks user chatroom where you can get information from other users. You can also look the information up on the...

News: LEGO Robotic Monster Chess

The battery-operated, Bluetooth-controlled pieces use downward-facing sensors to read grids built into the individual squares on the board. They then communicate with the controlling computer to keep track of their location in relation to other pieces. The computer tells each piece which direction to go, and how far, on its turn.

How To: Coach Young Sports Players with Differing Abilities

On sports teams, especially youth sports teams, the players are never one and the same. Young athletes are all different, which means they all have different skills and abilities out on the field or in the arena. As a coach, you can't treat them as a whole, but you need to treat these young players as individuals of a whole. This video covers some practices and techniques, as well as gives advice for better coaching skills for teaching a "team". This is coach psychology.